How Cannabis Can Support the Hormonal Transition of Transgender People

Medicinal cannabis is gaining ground as an ally in the hormonal treatment of transgender individuals, helping with sleep, anxiety, and well-being

Published on 11/20/2025

Como a cannabis pode apoiar a transição hormonal de pessoas trans

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Medicinal cannabis is beginning to gain ground as an ally in the gender transition process, especially for individuals undergoing hormonal therapy. 


According to the El Planteo website, phytocannabinoids such as CBD and THC can help reduce side effects, improve well-being, and support emotional balance during this intense and transformative stage.


Relief of Common Hormonalization Symptoms


Hormonal transition involves profound physical and emotional changes. Many transgender individuals report anxiety, mood swings, sleep difficulties, and pain, symptoms that can be alleviated with the therapeutic use of cannabis. 

Learn More - Young people report using cannabis to deal with adversities
 


According to biomedical scientist Bárbara Arranz, cited by El Planteo, CBD has stood out for its anxiolytic and anti-inflammatory action, while THC can act on hormonal regulation by interacting with endocannabinoid system receptors.
For some transgender women, CBD may have an even more significant impact, as some preliminary studies show a potential effect on processes related to female hormones.


Complementary Use and Need for Care


Experts emphasize that cannabis does not replace hormonal therapy, but can function as support for quality of life, sleep, appetite, and emotional balance. However, its use should always be guided by professionals, as doses and responses vary from person to person and there are still few specific studies on cannabis in transgender populations.


With more research and proper access, cannabis can become an integral part of comprehensive care for transgender individuals in the transition process.

With information from El Planteo.
 

How Cannabis Can Support the Hormonal Transition of Transgender People