Brazilian researchers create portable sensor for rapid detection of synthetic cannabinoids in Vapes
Device promises to expedite the identification of dangerous drugs in vape liquids and biological samples, offering a new tool for public health and safety
Published on 09/16/2025

Portable Sensor. Image: FCF/ Unicamp
The e-liquid in electronic cigarettes, even without containing illicit substances, can cause serious health damage. The nicotine concentration in these products often exceeds that of conventional cigarettes, promoting rapid dependence. In Brazil, these devices are prohibited, which means they undergo no quality control, increasing risks for users.
The scenario is also concerning when it comes to the use of synthetic cannabinoids in electronic cigarettes. Created in the laboratory to mimic the effects of tetrahydrocannabinol (THC) - the main psychoactive component of marijuana - these substances are much more potent and can trigger seizures, psychotic episodes, and even fatal overdoses.
"What we are seeing is a chemical race. Clandestine groups produce drugs with increasingly potent structures, requiring minimal doses. As there is no labeling, the user consumes without knowing what they are ingesting," warns Luciano Arantes, researcher and member of the management committee of the National Institute of Science and Technology on Psychoactive Substances (INCT-SP), in a note from the State University of Campinas (Unicamp).
A Brazilian solution
To combat the spread of synthetic cannabinoids, Brazilian researchers, in international partnership, have developed a portable sensor. The device is capable of accurately detecting these substances in electronic cigarette liquids and in biological fluids, such as saliva.
The device uses a boron-doped diamond electrode, which connects to a portable potentiostat, attachable to a cell phone. The result is a graph that identifies and quantifies the substances present in the sample with very high sensitivity.
Tested with two of the most dangerous synthetic cannabinoids, the sensor detected minimal concentrations (in the order of 0.2 µM), even amidst high doses of nicotine.
Impact on public health and harm reduction
According to the researchers, the sensor's applications range from criminal forensics to public health. It can be used in emergency overdose care and in preventive actions, such as those carried out in partnership with the "BACO Project," which analyzes the use of new psychoactive substances at parties and festivals.
The future of detection and technology adaptation
The method's adaptability is a strong point. The team is already expanding the technology to detect other classes of synthetic drugs, such as LSD analogs, cathinones, and phenylethylamines.
The research was supported by FAPESP and involved collaboration with experts from Unicamp, who provided real samples collected under the BACO Project, a partnership with the Ministry of Justice and Public Security (MJSP).
With information from FCF