Can CBD Interact with Contraceptives?

By El Planteo

We have plenty of scientific evidence supporting the multiple therapeutic uses of CBD. However, there is some uncertainty about the long-term effects of using the compound and the impact of taking it in conjunction with other supplements or medications.

When it comes to the interaction between CBD and contraceptives, there are still many unanswered questions. So, what do we know for sure?

CBD, or Cannabidiol, is a non-toxic cannabinoid, or chemical compound, found in the cannabis plant.

CBD can be used to treat anxiety and manage pain, among numerous other conditions: from seizures to arthritis and much more. However, unlike THC (the cannabinoid responsible for the psychoactive effects of cannabis), consuming CBD will not make you feel "high".

The WHO Expert Committee on Drug Dependence (World Health Organization) concluded that, in its pure state, "cannabidiol does not appear to have potential for abuse or harm". However, you may experience dry mouth, fatigue, or diarrhea and, in some rare cases, it is believed to cause liver damage.

According to the limited available data, there may be adverse effects from the combination of CBD and certain contraceptives. Specifically, contraceptives containing estrogen or Ethinylestradiol (synthetic estrogen) - which are the majority.

Interactions

The interaction between CBD and estrogen can decrease the effectiveness of contraceptives, shorten the elimination time of cannabis from the body, and cause drowsiness, as well as breakthrough bleeding.

Progestin-only contraceptives, like the DMPA injection, may be a more effective option when you are a regular CBD user.

The decreased effectiveness of combined contraceptives with CBD can also be exacerbated by tobacco consumption. It should be noted that using contraceptives with tobacco has been shown to reduce the effectiveness of the former, as well as increase the risk of multiple health problems.

Possibility vs. Probability

It should be noted that when examining contraceptive leaflets, you will find exhaustive lists of potential adverse effects. This includes everything from bleeding gums to eye discomfort and sensitivity to the sun. The popular contraceptive Yaz warns: "Stay away from the sun." [...] Do not use sun lamps or tanning beds/booths."

Do all experience these negative reactions? No. Do the majority of users experience negative reactions? No. But, for good reason, these warnings exist.

Conclusion

Currently, there is not enough information to make definitive statements. There are some isolated studies, but nothing is conclusive yet. However, current evidence suggests that using CBD in addition to using contraceptives decreases contraceptive performance. However, there is no information on the magnitude of this effect. If potency were reduced by 0.05%, for example, it would be a significant difference compared to a 20% reduction. We still do not have an answer. However, if you use CBD regularly, it is advisable that you use progestin contraceptives and/or condoms, or some other contraceptive method and remember, always seek a medical professional to assist you on this path.