Cannabisol, canabitwinol and canabizetol: the new generation of cannabinoids

Researchers identify three new cannabinoids, cannabisol, canabitwinol, and canabizetol, with promising therapeutic properties, expanding the boundaries of science on Cannabis sativa

Published on 10/29/2025

Cannabisol, canabitwinol e canabizetol: a nova geração de canabinoides

Science discovers novel cannabis compounds with potential anti-inflammatory action | CanvaPro

The discovery of three new compounds derived from cannabis, cannabisol, canabitwinol, and canabizetol, is sparking the interest of the scientific community for their therapeutic potential. 

According to NewsWeed, these newly identified cannabinoids, described in a recent study published in ACS Omega, belong to a category that is still largely unexplored: dimeric cannabinoids, molecules formed by the fusion of two similar chemical structures.


New molecules, new possibilities


Cannabisol (CBL-C6), canabitwinol (CBTW), and canabizetol (CBZ) were found in different samples of Cannabis sativa and exhibit unique chemical properties.

According to the researchers, the dimeric structure of these molecules may confer greater stability and bioactivity, paving the way for studies on their use in chronic inflammations, neurological disorders, and autoimmune diseases.

The study indicates that canabitwinol demonstrated promising antioxidant characteristics, while canabizetol may act as a potent anti-inflammatory agent. Cannabisol, the first of its category to be isolated, has shown relevance for research related to neuroprotection and cell regeneration.


Mapping the metabolome of Cannabis sativa


The identification of these substances was made possible thanks to the advancement of mass spectrometry and chromatography techniques, which allow for the precise mapping of the plant's

Cannabisol, canabitwinol and canabizetol: the new generation of cannabinoids