Imagine living daily with intense pain, constant fatigue, and uncertainty about what tomorrow will bring. This is the reality for millions of people diagnosed with autoimmune diseases, conditions in which the immune system starts attacking the body itself. Amidst the limitations of traditional treatments, a new hope is gaining momentum: medicinal cannabis.

A study conducted by researcher Gustavo Ianke, in the Pharmacy course at the Federal University of São Paulo (Unifesp) - Diadema Campus, analyzed the therapeutic potential of the plant in managing diseases such as multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus, and Crohn's disease. The study points to promising advancements but also highlights the challenges that still need to be overcome.

Cannabis and the immune system

According to the research, compounds like cannabidiol (CBD) and tetrahydrocannabinol (THC) interact with the endocannabinoid system, which regulates functions such as pain, inflammation, and immune response. This interaction allows for the reduction of chronic symptoms, such as joint pain, muscle stiffness, and persistent inflammations, which are often not controlled with conventional therapies.

Medications already approved in countries like Brazil, such as Mevatyl®, have shown efficacy in patients with multiple sclerosis, reducing muscle spasms and improving sleep quality. In the case of Crohn's disease, clinical trials have shown that up to 45% of patients went into remission after using cannabis.

Limitations and challenges

Despite the positive results, the study highlights significant obstacles. These include the lack of standardized doses, the scarcity of robust clinical studies, and the social stigma still surrounding the plant. Additionally, regulatory barriers hinder patients' access to safe and quality treatments.

“Although cannabis presents itself as an innovative and adjunct therapy, its consolidation depends on public policies, clear regulations, and more scientific research,” the study points out.

A therapy in progress

The study concludes that medicinal cannabis can be a game-changer in the treatment of autoimmune diseases, but its effective implementation requires a balanced approach. This includes collaboration among researchers, physicians, and policymakers to ensure safety, efficacy, and accessibility.