Medicinal Cannabis Shows Potential in Relieving Insomnia, Studies Say

Sleeping well is still a challenge for 45% of the global population according to the WHO. But science is beginning to point to paths beyond traditional prescription drugs. New research suggests that cannabis-based medications, especially those containing THC or combinations of cannabinoids, may be promising allies in the fight against insomnia.

Two recent studies have caught attention. A meta-analysis published in Sleep Medicine Reviews analyzed six clinical trials with 1,077 participants and found a significant improvement in sleep quality in those who used formulations without CBD, such as isolated THC or mixed with other cannabinoids.

Another study from Imperial College London, with 124 UK patients followed for 18 months, reported not only advances in sleep but also reductions in symptoms of anxiety, depression, and pain.

Today, about one in three people worldwide struggle to sleep well, and 10% of adults meet the criteria for insomnia. Traditional treatment options, such as cognitive-behavioral therapy or prescribed medications, are often difficult to access and can lead to adverse effects or long-term dependence.

Stronger Results with THC and Mixed Cannabinoids

The systematic review pointed out that, in clinical trials, improvements were more significant in people diagnosed with insomnia or poor sleep quality. Formulations without CBD showed a medium to large effect, while the exclusive use of cannabidiol did not show significant benefits, challenging the popular perception that CBD alone is a potent sleep inducer.

Despite the encouraging results, researchers emphasize that robust trials are still needed to define the ideal dosage, safe formulations, and long-term effects.

Real-World Evidence

In the British study published in PLOS Mental Health, patients treated with medicinal cannabis reported consistent gains in sleep quality over a year and a half, with only 9% mentioning mild adverse effects, such as fatigue and dry mouth.

“Our study showed that treating insomnia with cannabis-based medicinal products was associated with sustained improvements in subjective sleep quality and anxiety symptoms,” said Dr. Simon Erridge, research director at Curaleaf Clinic.

For him, these findings reinforce the role of medicinal cannabis as an alternative in cases where conventional methods have failed, but highlight the importance of continuous monitoring and individualized treatment plans.

With information from Cannabis Health News.