Ciência & Tecnologia

Study shows that cannabis oil has efficacy comparable to Lorazepam for insomnia

Research published in Sleep Medicine: X reveals that the herbal remedy improves sleep quality and quality of life with safety similar to benzodiazepines

Study shows that cannabis oil has efficacy comparable to Lorazepam for insomnia
The study concluded that cannabis oil and the Thai herbal remedy Suk-Sai-Yat have efficacy comparable to Lorazepam in the treatment of chronic insomnia. Image: Canva Pro

A new randomized clinical trial, published in the scientific journal Sleep Medicine: X, revealed promising data on integrative therapies. The study concluded that cannabis oil and the Thai herbal medicine Suk-Sai-Yat have efficacy comparable to Lorazepam in the treatment of chronic insomnia.

The research, made available online in January 2026, evaluated 60 adults over a four-week period. The main focus was to monitor the evolution in sleep quality and quality of life of participants subjected to different therapies.

 

Study methodology with cannabis oil


The methodology divided patients into three distinct groups, who received either the Thai herbal remedy, cannabis oil (Deja formula), or conventional allopathic medication.

The central objective was to compare the safety and effectiveness of integrative therapies against treatment with benzodiazepines. The latter are often used for sleep disorders but have known side effects.

 

Results and impact of cannabis oil on sleep


After four weeks, all groups showed significant improvements in the Pittsburgh Sleep Quality Index (PSQI). The group treated with cannabis oil saw its average score drop from 13.6 to 3.68.

This result is statistically similar to that observed in the Lorazepam group. The data indicate, therefore, that there was no inferiority in the use of cannabinoid therapy compared to the traditional medication.

 

Safety and quality of life with cannabis oil use


In addition to direct efficacy on sleep, researchers observed other gains. Quality of life improved more significantly in patients who used integrative therapies, including cannabis oil, compared to those who used conventional medication.

In terms of safety, the scenario was also positive. Only mild adverse events were reported in all groups analyzed during the study, reinforcing the safe profile of the tested substances.

The authors concluded that both Suk-Sai-Yat and Cannabis sativa oil represent viable options for managing insomnia. The evidence suggests that these non-benzodiazepine alternatives offer robust clinical benefits for patients seeking integrative treatments.

 

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