Full Spectrum Cannabidiol: Why the Complete Cannabis Formulation Improves Chronic Pain Treatment

Medications based on medicinal cannabis continue to gain ground in Brazil, especially among patients with chronic pain seeking more effective alternatives with fewer side effects. 

Within this scenario, full spectrum cannabidiol emerges as a therapeutic alternative that combines various natural compounds from the plant — such as cannabinoids, terpenes, and flavonoids — capable of acting synergistically and enhancing clinical results.

What Sets Full Spectrum Apart in Pain Treatment
 

While products with isolated CBD undergo a purification process that removes other plant elements, full spectrum extracts maintain cannabinoids, terpenes, and small concentrations of THC, within the limit allowed by Anvisa (up to 0.2%).

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This combination gives rise to the so-called entourage effect, a synergy between compounds that enhances the therapeutic response.

Acting directly on the receptors of the endocannabinoid system, present in the central nervous system and responsible for regulating functions such as pain, mood, inflammation, and immunity, the complete formulation can help the body restore physiological balance.

Lower Doses, Increased Tolerance, and Better Clinical Response

Studies indicate that patients often tolerate full spectrum extracts well, often requiring lower doses to achieve the same results as products with isolated CBD.

According to experts, this difference is directly linked to the entourage effect, which enhances the combined action of plant compounds. To achieve the same therapeutic result, doses of full spectrum medications can be up to four times lower than those of products with isolated CBD, which also contributes to reducing side effects such as postural hypotension, nausea, loss of appetite, and insomnia.

Cannabidiol has proven to be an important ally in managing chronic pain, such as those related to fibromyalgia, endometriosis, traumatic injuries, and persistent syndromes.

Dose Adjustment and Monitoring are Essential

Full spectrum extracts, containing THC, require even more care during the titration phase. The medical protocol includes:

• - conducting exams before starting treatment;
• - weekly monitoring during dose adjustment;
• - always starting with the lowest possible dose, increasing gradually.

The ideal dose can provide up to 80% improvement in symptoms. In some cases, after this milestone, it is possible to reduce or even discontinue other medications over a period of about three months.