Periodontal Disease and the Therapeutic Use of Cannabis in Menopausal Women

Learn how medicinal cannabis can act as an effective alternative in controlling pain, inflammation, and preserving bone health

Published on 10/08/2025

Doença periodontal e o uso terapêutico da cannabis em mulheres na menopausa

Menopause can worsen periodontal disease, bringing gum inflammation and discomfort | CanvaPro

There are phases in a woman's life when the body calls for a gentler approach, and menopause is one of them. A period in which many of us experience transformations that go far beyond hot flashes, reaching even oral health. 


Dry mouth, gum bleeding, and even bone loss are silent symptoms of a process that affects hormones, tissues, and emotions.


But the good news is that new therapeutic possibilities are beginning to emerge on this care path. Among them, medicinal cannabis has gained prominence as a promising ally in combating periodontal disease, an inflammatory condition that affects the supporting tissues of the teeth.


Explaining to us is dentist Rafaela A. da Rosa, a specialist in Orofacial Pain, Implantology, and therapeutic use of cannabis in dentistry. “Menopause is marked by a sharp drop in estrogen, a hormone that directly influences periodontal health. This deficiency stimulates pro-inflammatory substances and accelerates bone resorption, favoring the loss of tooth insertion,” explains Rafaela.

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The situation worsens with reduced salivary flow and changes in oral microbiota, making the environment more vulnerable to bacteria and persistent inflammations. And it is precisely there that cannabinoids, compounds derived from cannabis sativa, can make a difference.


Cannabis and the Power to Restore Balance


 

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Dr. Rafaela da Rosa explains that cannabidiol can favor the repair of healthy gum tissues and cells | Photo: Personal Archive

The anti-inflammatory and analgesic properties of cannabidiol (CBD) have been widely studied in dentistry. Initial research indicates that the compound acts by reducing inflammatory cytokines and modulating specific body receptors, such as CB2, helping to control gum inflammation and orofacial pain.

“CBD may even favor tissue repair, stimulating healthy gum cells and reducing bone loss in experimental models,” says the dentist.


Furthermore, there is evidence that the therapeutic use of cannabis may contribute to overall bone health, which is especially relevant for menopausal women, a phase where osteoporosis and alveolar bone resorption become more common.


But the specialist emphasizes caution: “Most studies are pre-clinical. We need more robust research in humans to define safe protocols, optimal doses, and more effective administration routes.” 


Integrated Care: Science, Balance, and Empathy


For those who wish to combine conventional dental treatment with the therapeutic use of cannabis, Rafaela recommends an integrated approach that combines science, medical monitoring, and attention to detail.


She advises against inhalation, which can worsen dry mouth and gum inflammation, and suggests prioritizing controlled oral forms, such as oils or quality-certified gums. She also warns of possible drug interactions, as CBD can alter the metabolism of some drugs, requiring medical monitoring.

“Each woman is unique, and treatment must respect this singularity. The use of cannabis should be gradual, with low doses and close monitoring, always observing the effects and clinical evolution,” she emphasizes.


Furthermore, basic care is always essential: proper brushing, flossing, constant hydration, and regular visits to the dentist remain the foundation of a healthy smile.


Caring for the Mouth is also Caring for Oneself


Menopause is an invitation to internal listening, a moment to rediscover one's body and allow oneself to embrace new forms of care. For many women, cannabis emerges not only as a therapeutic alternative but as a symbol of reconnection with well-being. “It's about restoring comfort, self-esteem, and quality of life,” she concludes.