What is Migraine? Migraine, also known as a headache, is a neurological condition characterized by recurrent episodes of intense head pain. It is usually a throbbing or pulsating pain, of moderate to severe intensity, affecting one side of the head. The episodes are often accompanied by symptoms such as nausea, as well as sensitivity to light and sound.

When the throbbing pain of a migraine crisis paralyzes the day, any hope of relief gains special weight. This is exactly what patients felt in the first placebo-controlled study evaluating vaporized cannabis for the treatment of acute migraine: significant improvement in pain and symptoms in just two hours.

First Encouraging Results

The research, conducted by the University of California in San Diego (UCSD), evaluated 92 patients with a history of migraines. They received different forms of vaporized cannabis (THC, CBD, or the combination of both) or placebo during pain crises.

The results showed that the THC and CBD combination was the most effective, achieving significantly higher rates of pain relief and relief from the most bothersome symptoms, such as photophobia and phonophobia, compared to the placebo. More than 34% of participants treated with the combination reported complete absence of pain in two hours, compared to 15.5% in the placebo group.

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Safety and Next Steps

Although side effects such as drowsiness and euphoria were observed, no serious adverse events were recorded. Neurologist Nathaniel M. Schuster, responsible for the study, emphasized that the findings reinforce the potential of cannabis as a therapeutic alternative for patients who do not respond to conventional options.

However, experts caution: further studies with larger populations and long-term follow-up are needed to assess the safety of frequent cannabis use in migraine treatment.

With information from Medscape.